Dr. Francesc Graus obtained his MD degree in 1976 and his PhD in 1982 at the Universitat Autónoma de Barcelona. He completed his residency of Neurology in Barcelona and the fellowship in Neuro-Oncology at the Memorial Sloan-Kettering Cancer Center, Nueva York, USA. Until 2018 he was the chief of the neurology service of the Hospital Clinic, Barcelona and coordinator the neuroimmunology program of the Institut d’Investigació Biomèdica August Pi i Sunyer (IDIBAPS) affiliated to the Hospital Clinic. He is presently Emeritus investigator of IDIBAPS.
The area of research of Dr. Graus has been the paraneoplastic neurological syndromes. He led the panel of experts that defined for the first time strict criteria for their diagnosis. His research has been important for the confirmation of the immune hypothesis that the underlying tumor triggers and autoimmune attack to the nervous system causing the neurological dysfunction. The antibodies he has identified (Hu, Tr, Sox1) are now widely used for the diagnosis of these syndromes. In the last years, he has been involved in the field of autoimmune encephalitis associated with antibodies against neuronal surface antigens. The research in this area led to the characterization of the anti-IgLON5 disease, an intriguing CNS disorder at the crossroad of autoimmunity and neurodegeneration.